Author

Nipam Patel
Email

Additional Author(s): April Dinwiddie

Published on SDB CoRe: Jan 17 2012

Organisms: Invertebrates
Embryonic Patterning: Axis Formation; Segmentation
Organism: Drosophila
Stage of Development: Embryo

Object Description

Lateral view (anterior to left, ventral down) of a blastoderm stage Drosophila melanogaster embryo immunostained for Fushi tarazu (red), Even-skipped (purple), and Snail (green).  Nuclei are stained with DAPI (blue).  Fushi tarazu and even-skipped are pair rule genes expressed in seven vertical stripes forming fourteen alternating bands that coincide with what will be the boundaries between future body segments in the adult fly. Snail is a transcriptional repressor expressed throughout the presumptive mesoderm that downregulates expression of ectodermal genes.

References

Lawrence, P.A., Johnston, P., Macdonald, P., Struhl, G. Borders of parasegments in Drosophila embryos are delimited by the fushi tarazu and even-skipped genes. Nature, 1987, 328:440-442.

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